新城疫病毒血凝素神经氨酸酶的蛋白水解激活涉及一种糖肽的丢失。
Proteolytic activation of the haemagglutinin-neuraminidase of Newcastle disease virus involves loss of a glycopeptide.
作者信息
Garten W, Kohama T, Klenk H D
出版信息
J Gen Virol. 1980 Nov;51(Pt 1):207-11. doi: 10.1099/0022-1317-51-1-207.
PMID:7463006
Abstract
The uncleaved (HN0) and the cleaved (HN) forms of the haemagglutinin-neuraminidase glycoprotein of Newcastle disease virus (NDV), strain Ulster, were analysed by polyacrylamide gel electrophoresis under reducing and non-reducing conditions. When HN0 is converted into HN, a glycopeptide with an apparent mol. wt. of about 8000, which is not found in the mature spike, is removed.
摘要
在还原和非还原条件下，通过聚丙烯酰胺凝胶电泳对新城疫病毒（NDV）阿尔斯特株血凝素神经氨酸酶糖蛋白的未切割（HN0）和切割（HN）形式进行了分析。当HN0转化为HN时，会去除一种表观分子量约为8000的糖肽，这种糖肽在成熟的刺突中不存在。
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