Reinhardt K
Z Orthop Ihre Grenzgeb. 1980 Oct;118(5):713-20. doi: 10.1055/s-2008-1053530.
The article reports on two cases of a typical necrosis of the head of the femur, known as "idiopathic necrosis of the femoral head". Hyperuricaemia was present in both cases. In the first female patient, scintigraphy showed accumulation of activity unilaterally in the region of the ankle joint without any pathological x-ray finding in that region. The necrosis of the head of the femur was atypically associated with a lateral narrowing of the joint space and apposition of the bones at the lateral joint edges. Angiography did not yield any abnormal finding in the hip joint. In the case of the second (male) patient, the necrosis of the femoral head was combined with diaphyseal osteonecrotic changes bilaterally, distal to the femoral shaft, and there was also a diffuse decalcification, not recorded so far, metaphyseally distal to the femoral shaft and proximal at the shaft of the tibia, reaching to the epiphyseal cicatrices. Hyperuricaemia was combined with hyperlipidaemia. In both patients, the hyperturicaemia dropped to normal levels under appropriate medication; in the second patient, this was also true of the hyperlipidaemia and hypercholesterolaemia. No further progress was seen from the time the blood levels had become normal.
本文报道了两例典型的股骨头坏死病例，即“特发性股骨头坏死”。两例患者均存在高尿酸血症。在首例女性患者中，骨闪烁显像显示踝关节区域单侧有放射性聚集，但该区域X线检查未发现任何病理改变。股骨头坏死伴有非典型的关节间隙外侧变窄以及关节外侧边缘骨质增生。血管造影未发现髋关节有任何异常。在第二例（男性）患者中，股骨头坏死合并双侧股骨干骺端远端的骨干骨坏死改变，并且在股骨干骺端远端和胫骨干近端还存在一种迄今未记录到的弥漫性脱钙，延伸至骨骺瘢痕。高尿酸血症合并高脂血症。在适当药物治疗下，两名患者的高尿酸血症均降至正常水平；在第二例患者中，高脂血症和高胆固醇血症也恢复正常。自血液水平恢复正常后未再出现进一步进展。
