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[重型颅脑创伤患者弥散性血管内凝血综合征的诊断与治疗]

[Diagnosis and treatment of DIC syndrome in patients with severe craniocerebral trauma].

作者信息

Churliaev Iu A, Lychev V G, Epifantseva N N, Pavlenko A A, Kovalenko V M, Potekhin K G, Karagaeva L G, Suvorova T Iu

出版信息

Anesteziol Reanimatol. 1995 Jul-Aug(4):29-33.

PMID:7486191
Abstract

The hemostasis parameters are compared in 32 patients with slight (14-15 Glasgow score) and 114 with grave craniocerebral injury (3 to 7 Glasgow score) on days 1, 3, 5, and 7 after the injury. Assessment of hemostasiograms revealed a regular development of disseminated intravascular blood coagulation (DIC) in patients with grave craniocerebral injury, whereas in patients with slight injury the changes in the hemostasis system were compensatory. Early (starting from day 1) addition of anticoagulants, disaggregants, and fresh-frozen plasma to treatment protocols are advisable for patients with grave craniocerebral injuries.

摘要

在受伤后的第1、3、5和7天,对32例轻度颅脑损伤(格拉斯哥评分为14 - 15分)患者和114例重度颅脑损伤(格拉斯哥评分为3至7分)患者的止血参数进行了比较。止血图评估显示,重度颅脑损伤患者中弥散性血管内凝血(DIC)呈规律性发展,而轻度损伤患者的止血系统变化具有代偿性。对于重度颅脑损伤患者,建议在治疗方案中早期(从第1天开始)添加抗凝剂、抗聚集剂和新鲜冷冻血浆。

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