Emery C L, Morway L F, Chung-Park M, Wyatt-Ashmead J, Sawady J, Beddow T D
Department of Pathology, Case Western Reserve University at MetrolHealth Medical Center, Cleveland, Ohio 44109, USA.
Arch Pathol Lab Med. 1995 Nov;119(11):1032-7.
This study examines the indications for performing the Kleihauer-Betke (KB) test and makes recommendations for its use. Results of 523 KB tests performed during 1993 at our hospital (Cleveland, Ohio) are reviewed in conjunction with surgical pathology reports of placental findings, obstetric records, and toxicology results. We conclude that the KB test should be performed following a positive screening test on all Rh negative mothers of Rh positive infants. Additional indications include cases of maternal trauma, unexplained increased maternal alpha-fetoprotein levels, fetal distress with abnormal heart tracings, intrauterine fetal death, and cases of unexplained neonatal anemia. We note that the KB test should not be performed to detect suspected placental abruption.
本研究探讨了进行克莱豪尔-贝特克（KB）试验的指征，并对其使用提出建议。结合胎盘检查的外科病理报告、产科记录和毒理学结果，回顾了1993年在我院（俄亥俄州克利夫兰）进行的523次KB试验的结果。我们得出结论，对于所有Rh阳性婴儿的Rh阴性母亲，在筛查试验呈阳性后应进行KB试验。其他指征包括母亲创伤病例、不明原因的母亲甲胎蛋白水平升高、伴有异常心电图的胎儿窘迫、宫内胎儿死亡以及不明原因的新生儿贫血病例。我们注意到，不应进行KB试验以检测疑似胎盘早剥。
