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Histopathology of C57BL/6 mice inoculated orally with Mycobacterium paratuberculosis.

作者信息

Veazey R S, Taylor H W, Horohov D W, Krahenbuhl J L, Oliver J L, Snider T G

机构信息

Department of Veterinary Pathology, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803, USA.

出版信息

J Comp Pathol. 1995 Jul;113(1):75-80. doi: 10.1016/s0021-9975(05)80071-4.

Abstract

The susceptibility of C57BL/6 mice to oral inoculation with Myobacterium paratuberculosis was evaluated histopathologically. Granulomatous lesions containing acid-fast bacteria developed in the mesenteric lymph nodes in over 50% of the mice by 11 months after inoculation. The results suggest that C57BL/6 mice may be useful for studying infection, pathogenesis, and other aspects of paratuberculosis.

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