Veazey R S, Taylor H W, Horohov D W, Krahenbuhl J L, Oliver J L, Snider T G
Department of Veterinary Pathology, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803, USA.
J Comp Pathol. 1995 Jul;113(1):75-80. doi: 10.1016/s0021-9975(05)80071-4.
The susceptibility of C57BL/6 mice to oral inoculation with Myobacterium paratuberculosis was evaluated histopathologically. Granulomatous lesions containing acid-fast bacteria developed in the mesenteric lymph nodes in over 50% of the mice by 11 months after inoculation. The results suggest that C57BL/6 mice may be useful for studying infection, pathogenesis, and other aspects of paratuberculosis.