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失语症的解剖学与临床考量:体层X线密度测定法的价值(作者译)

[Anatomical and clinical considerations in aphasia: the value of tomodensitometry (author's transl)].

作者信息

Barat M, Constant P, Mazaux J M, Caillé J M, Arné L

出版信息

Rev Neurol (Paris). 1978 Oct;134(10):611-7.

PMID:749120
Abstract

Tomometric tests were carried out in 54 patients with a clinical picture of stabilized or regressive aphasia, some time after the initial episode. The correlation between clinical and topographic findings were satisfactory in 90 p. 100 of the cases. The frequency of lesions extending into several lobes (70 cases) and of multiple lesions is stressed. There is a significant relationship between the severity of the clinical findings during tomometric testing and the volume or multiplicity of the lesions. The progression of the disease after 6 months, as studied in 31 patients, was also related to the volume of the lesion, but was not influenced by the presence of diffuse atrophy, except where the disease was deteriorating. The value of tomometry in the study of aphasia involves 3 factors: precise clinical and lesional correlation, and the effect of the volume of the lesion on its initial severity and progression. In the future, tomometry should enable a correlative symptomatic study of aphasic disorders to be made.

摘要

对54例临床表现为失语症稳定或消退的患者在初次发病一段时间后进行了眼压测量测试。在90%(即100例中的90例)的病例中,临床和影像学检查结果之间的相关性令人满意。文中强调了病变延伸至多个脑叶(70例)和多发病变的频率。眼压测量测试期间临床检查结果的严重程度与病变的体积或多发性之间存在显著关系。在31例患者中进行研究发现,6个月后疾病的进展也与病变体积有关,但不受弥漫性萎缩的影响,除非疾病正在恶化。眼压测量在失语症研究中的价值涉及三个因素:精确的临床与病变相关性,以及病变体积对其初始严重程度和进展的影响。未来,眼压测量应能够对失语症障碍进行相关的症状学研究。

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