Jaffray D A, Chawla K, Yu C, Wong J W
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI 48073, USA.
Int J Radiat Oncol Biol Phys. 1995 Dec 1;33(5):1273-80. doi: 10.1016/0360-3016(95)00271-5.
Due to the poor quality of megavoltage (MV) radiographs, detection and assessment of discrepancies in radiation field placement are difficult. Furthermore, the high imaging dose required to produce the megavoltage radiograph prohibits frequent image acquisition, particularly for those fields that require the use of an "open-field" exposure. For these small, or conformal, radiation fields, an alternate method of verifying field placement is required if the out-of-field dose is to be minimized. An open-field image acquired with a kilovoltage (kV) source would (a) deliver a very low patient dose, (b) increase the visibility of bony landmarks, and (c) simplify intercomparison of portal and prescription images. This article describes the development of a dual-beam imaging system that produces diagnostic quality "double-exposure" portal images for verifying radiation field placement.
The dual-beam system consists of a kV x-ray tube mounted on the gantry of a medical linear accelerator. The kV beam shares the same isocenter (+/- 1 mm) as the treatment beam but is at 45 degrees to the central axis. Both the kilovoltage and megavoltage images are collected with a fluoroscopic imaging system that uses a low-noise CCD camera to accumulate the light emitted from a phosphor screen. Two 45 degrees mirrors are used to remove the CCD camera from the x-ray beam. The light integration on the CCD array is controlled by a mechanical shutter, allowing easy synchronization with the radiation exposures. The camera is shielded by a lead housing to reduce the number of x-rays reaching the CCD array. A conventional thickness phosphor screen is used for both the kV and MV exposures. In the dual-beam imaging procedure, an open-field kV radiograph is acquired with the patient in treatment position. Immediately following, a MV image is acquired with the beam-defining blocks in position. Summation of the two images produces an online double-exposure image. The anatomical information in either the kV or MV image can be emphasized by weighting the images appropriately. This system was used to acquire MV and kV images of both a contrast-detail phantom and a Rando head phantom. Dual-beam images were also acquired for a pituitary treatment, demonstrating the feasibility and usefulness of the dual-beam technique.
Analysis of the contrast-detail images produced with the MV and kV beams shows the expected advantage of using the kV x-ray beam. Images of a Rando head phantom confirm these results. A clinical demonstration of the dual-beam system for verifying the delivery of a pituitary field is shown. The quality of the dual-beam image is similar to the prescription (simulation) image, contains a larger anatomical region, and delivers a lower integral dose to the patient. In addition, the kV beam also enhances the visibility of small markers implanted in the prostate.
A dual-beam imaging system has been developed for the radiographic verification of small, conformal fields. This development demonstrates the advantages and feasibility of using a kV x-ray beam in combination with the treatment beam to improve the accuracy of detecting patient setup errors.
由于兆伏级(MV)射线照片质量较差,很难检测和评估辐射野放置的差异。此外,生成兆伏级射线照片所需的高成像剂量限制了频繁的图像采集,特别是对于那些需要使用“开放野”曝光的射野。对于这些小的或适形的辐射野,如果要将野外剂量降至最低,则需要一种验证射野放置的替代方法。用千伏(kV)源获取的开放野图像将(a)使患者剂量非常低,(b)增加骨性标记的可见性,以及(c)简化射野图像和处方图像的相互比较。本文描述了一种双束成像系统的开发,该系统可生成用于验证辐射野放置的具有诊断质量的“双曝光”射野图像。
双束系统由安装在医用直线加速器机架上的kV X射线管组成。kV束与治疗束共享相同的等中心(±1毫米),但与中心轴成45度角。千伏和兆伏图像均由荧光成像系统采集,该系统使用低噪声电荷耦合器件(CCD)相机来累积从磷光屏发射的光。使用两个45度镜将CCD相机移出X射线束。CCD阵列上的光积分由机械快门控制,便于与辐射曝光同步。相机由铅制外壳屏蔽,以减少到达CCD阵列的X射线数量。常规厚度的磷光屏用于kV和MV曝光。在双束成像过程中,患者处于治疗位置时获取开放野kV射线照片。紧接着,在射野界定块就位的情况下获取MV图像。将这两张图像相加可生成在线双曝光图像。通过适当加权图像,可以突出kV或MV图像中的解剖信息。该系统用于获取对比细节体模和兰多头部体模的MV和kV图像。还获取了垂体治疗的双束图像,证明了双束技术的可行性和实用性。
对MV和kV束产生的对比细节图像的分析显示了使用kV X射线束的预期优势。兰多头部体模的图像证实了这些结果。展示了双束系统用于验证垂体射野传递的临床示例。双束图像的质量与处方(模拟)图像相似,包含更大的解剖区域,并且向患者提供更低的积分剂量。此外,kV束还增强了植入前列腺的小标记的可见性。
已开发出一种双束成像系统,用于小的适形野的射线照相验证。这一进展证明了将kV X射线束与治疗束结合使用以提高检测患者摆位误差准确性的优势和可行性。