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功能孤立肾患者上尿路移行细胞癌的经皮电汽化术

Percutaneous electrovaporization of upper tract transitional cell carcinoma in patients with functionally solitary kidneys.

作者信息

Nakada S Y, Clayman R V

机构信息

Department of Surgery, University of Wisconsin Medical School, Madison, USA.

出版信息

Urology. 1995 Nov;46(5):751-5. doi: 10.1016/S0090-4295(99)80318-5.

Abstract

OBJECTIVES

We present the first reported experience using percutaneous electrovaporization with both a rollerball and the VaporTrode electrode of large upper tract transitional cell carcinoma (TCC) in 2 individuals with functionally solitary kidneys.

METHODS

Under general anesthesia and in the prone position, 2 patients underwent electrovaporization of upper tract TCC through upper pole percutaneous access. Using either a rollerball (Case 1) or the VaporTrode (Case 2) electrode at 200 W pure cutting current, the tumors were completely vaporized.

RESULTS

Average operating room time was 145 minutes. Hemostasis was excellent. No significant perioperative complications were noted. A nephrostogram at the end of the procedure revealed no extravasation in either case. There was no appreciable change in serum creatinine. Both patients received postoperative mitomycin (40 mg in 1000 cc normal saline over 20 hours) through the nephrostomy tube. One patient (Case 2) is completely free of disease via antegrade nephroscopy and biopsy at 2 weeks' follow-up. The other patient (Case 1) had two remaining focal areas of tumor via antegrade nephroscopy 3 weeks postoperatively; both lesions were treated with electrovaporization via a flexible electrode through the flexible cystoscope and the VaporTrode, respectively.

CONCLUSIONS

Percutaneous electrovaporization of upper tract TCC appears to provide a simple, rapid, and effective endosurgical treatment in properly selected patients. Long-term follow-up will be needed to assess this new treatment modality definitively.

摘要

目的

我们报道了首例对2例功能性孤立肾患者的上尿路移行细胞癌(TCC)使用滚球电极和VaporTrode电极进行经皮电汽化术的经验。

方法

在全身麻醉和俯卧位下,2例患者通过经皮上极穿刺对上尿路TCC进行电汽化术。使用滚球电极(病例1)或VaporTrode电极(病例2),在200W纯切割电流下,肿瘤被完全汽化。

结果

平均手术时间为145分钟。止血效果良好。未观察到明显的围手术期并发症。术后肾造影片显示两例均无外渗。血清肌酐无明显变化。两名患者均通过肾造瘘管在术后接受丝裂霉素(40mg溶于1000cc生理盐水中,持续20小时)治疗。一名患者(病例2)在术后2周通过顺行肾镜检查和活检完全无疾病。另一名患者(病例1)在术后3周通过顺行肾镜检查发现仍有两个肿瘤病灶;分别通过软性膀胱镜和VaporTrode使用软性电极对两个病灶进行了电汽化术治疗。

结论

经皮电汽化术治疗上尿路TCC似乎为合适选择的患者提供了一种简单、快速且有效的腔内手术治疗方法。需要进行长期随访以最终评估这种新的治疗方式。

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