Suppr超能文献

三尖瓣置换术中的瓣膜选择:25年经验

The valve choice in tricuspid valve replacement: 25 years of experience.

作者信息

Van Nooten G J, Caes F L, François K J, Taeymans Y, Primo G, Wellens F, Leclerq J L, Deuvaert F E

机构信息

Department of Cardiac Surgery, University Hospital of Gent, Belgium.

出版信息

Eur J Cardiothorac Surg. 1995;9(8):441-6; discussion 446-7. doi: 10.1016/s1010-7940(05)80080-6.

Abstract

This study reviews 146 consecutive patients who underwent tricuspid valve replacement (TVR) with 69 bioprostheses (porcine and bovine pericardial) and 77 mechanical ball, disc or bileaflet valves between 1967 and 1987. The mean age was 51.4 +/- 12.1 years. Preoperatively, 97% were in New York Heart Association (NYHA) functional class III or more and over 40% had undergone previous cardiac surgery. Hospital mortality was high (16.1%). Incremental risk factors for hospital death were preoperative icterus (P < 0.01), hepatomegaly (P = 0.02), NYHA functional class IV (P = 0.02) and male sex (P = 0.04) (univariate analysis). Ninety-eight percent of the hospital survivors were followed up for a mean of 92 months. Cumulative follow-up added up to 955 patient-years. There were 70 late deaths. The actuarial survival rate was 74% at 60 months and less than 25% at 14 years. Incremental risk factors for late death indicated by univariate analysis were the type of tricuspid prosthesis (Smel-off-Cutter and Kay-Shiley prostheses) (P = 0.04), the type of operative myocardial protection (normothermia and coronary perfusion) (P = 0.05) and preoperative NYHA functional class IV (P = 0.05). We conclude that TVR carries a high operative risk and poor long-term survival, both influenced by preoperative and perioperative variables. Bearing in mind the poor prognosis for TVR, we prefer a large-sized bioprosthesis, in view of its initial good durability and low risk of valve-related events. However, in patients with good life expectancy, a bileaflet mechanical prosthesis may be an acceptable alternative.

摘要

本研究回顾了1967年至1987年间连续接受三尖瓣置换术(TVR)的146例患者,其中69例使用生物瓣膜(猪心包和牛心包),77例使用机械球瓣、盘瓣或双叶瓣。平均年龄为51.4±12.1岁。术前,97%的患者处于纽约心脏协会(NYHA)功能分级III级或更高,超过40%的患者曾接受过心脏手术。医院死亡率很高(16.1%)。单因素分析显示,医院死亡的增量危险因素为术前黄疸(P<0.01)、肝肿大(P = 0.02)、NYHA功能分级IV级(P = 0.02)和男性(P = 0.04)。98%的医院幸存者接受了平均92个月的随访。累积随访时间总计955患者年。有70例晚期死亡。60个月时的精算生存率为74%,14年时低于25%。单因素分析显示,晚期死亡的增量危险因素为三尖瓣假体类型(Smel-off-Cutter和Kay-Shiley假体)(P = 0.04)、手术心肌保护类型(常温及冠状动脉灌注)(P = 0.05)和术前NYHA功能分级IV级(P = 0.05)。我们得出结论,TVR手术风险高,长期生存率低,均受术前和围手术期变量影响。考虑到TVR预后较差,鉴于其初始良好的耐用性和较低的瓣膜相关事件风险,我们更倾向于使用大型生物瓣膜。然而,对于预期寿命较长的患者,双叶机械瓣膜可能是一个可接受的选择。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验