Mangano D T
University of California, San Francisco, USA.
Curr Opin Cardiol. 1995 Sep;10(5):530-42. doi: 10.1097/00001573-199509000-00015.
Assessment of the patient with cardiovascular disease is a challenging problem, especially for the subset of patients undergoing surgery. Perioperative cardiac morbidity affects more than 1.5 million people annually in the United States, and consumes more than +20 billion per year in health care resources. Solution of the problem initially had been addressed using routine historical and clinical evaluations and risk indices. More recently, nonroutine preoperative cardiovascular testing has been recommended, including exercise and Holter electrocardiography, radionuclide ventriculography, stress echocardiography, and dipyridamole thallium scintigraphy. Each of these tests has strengths and limitations that are addressed in this review. Paradigms for preoperative assessment of high-risk patients, based on the presence of coronary disease and the functional status of the patient, are presented and discussed. Diagnostic and therapeutic approaches for patients at high risk remain challenging; the mandate is for large-scale clinical trials to evaluate both the therapeutic and cost effectiveness of new preoperative assessment strategies.
对心血管疾病患者进行评估是一个具有挑战性的问题,对于接受手术的患者群体而言尤其如此。在美国,每年有超过150万人受到围手术期心脏疾病的影响,每年消耗的医疗资源超过200亿美元。该问题最初通过常规的病史和临床评估以及风险指数来解决。最近,有人建议进行非常规的术前心血管检查,包括运动和动态心电图、放射性核素心室造影、负荷超声心动图和双嘧达莫铊闪烁显像。本综述阐述了这些检查各自的优缺点。文中还介绍并讨论了基于冠心病的存在和患者功能状态对高危患者进行术前评估的模式。高危患者的诊断和治疗方法仍然具有挑战性;当务之急是开展大规模临床试验,以评估新的术前评估策略的治疗效果和成本效益。