Diaconescu M R, Costea I, Terinte R, Diaconescu S, Covic M, Zbranca E
Clinica a IV-a Chirurgie, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.
Chirurgia (Bucur). 1995;44(1):27-34.
Secondary (renal) hyperparathyroidism appears in chronic renal failure, sometimes in patients on chronic dialysis. Other causes includes rickets and osteomalacia. These diseases are associated with poor calcium and vitamin D absorbtion from the small bowel. Two patients with chronic renal failure maintained on chronic haemodialysis from two and three years, respectively underwent subtotal parathyroidectomy: removal of three glands and preserving a half of a gland in situ. The diagnosis and surgical indication was made upon clinical (bone pain and severe itching), radiological (demineralisation, ectopic calcifications) and biochemical (hypercalcemia, hyperphosphoremia, increased values of alkaline phosphatases) arguments. Postoperatively the improvement is defined by a return to normal in the clinical, laboratory and radiological parametres. The most appropriate operation for secondary hyperparathyroidism is still unresolved one of two techniques is performed according to the preference of the surgeon: subtotal parathyroidectomy or total parathyroidectomy with autotransplantation of parathyroid fragments into forearm muscle.
继发性(肾性)甲状旁腺功能亢进出现在慢性肾衰竭患者中,有时也见于接受长期透析的患者。其他病因包括佝偻病和骨软化症。这些疾病与小肠对钙和维生素D的吸收不良有关。两名分别接受了两年和三年长期血液透析的慢性肾衰竭患者接受了甲状旁腺次全切除术:切除三个腺体并原位保留半个腺体。诊断和手术指征基于临床(骨痛和严重瘙痒)、放射学(骨质脱矿、异位钙化)和生化(高钙血症、高磷血症、碱性磷酸酶值升高)依据做出。术后的改善通过临床、实验室和放射学参数恢复正常来界定。对于继发性甲状旁腺功能亢进,最合适的手术方式仍未确定,两种技术中的一种会根据外科医生的偏好进行:甲状旁腺次全切除术或甲状旁腺全切除术并将甲状旁腺碎片自体移植到前臂肌肉中。