Pelz D M
Department of Diagnostic Radiology, University of Western Ontario, London, Canada.
Baillieres Clin Neurol. 1995 Aug;4(2):297-315.
Interventional neuroradiology is a dynamic subspecialty which is rapidly gaining new applications in the treatment of neurological diseases. The most common therapeutic role is still in the treatment of brain AVMs, aneurysms and fistulae in close association with neurosurgical support. Endovascular treatment of aneurysms with thrombogenic coils is a promising technique which can be performed with low morbidity. The goal of complete aneurysm occlusion, including the neck, has not yet been achieved in all cases and the procedure has not been shown to possess clear advantages over surgical clipping. Pre-operative embolization of tumours and spinal lesions are common procedures in some centres. Angioplasty and papaverine infusion for treatment of cerebral vasospasm are being performed in most neurosurgical teaching centres. Although angiographic results are often impressive, corresponding clinical improvement is not always seen, particularly when treatment is delayed. Thrombolysis for treatment of acute stroke and angioplasty for treatment of cerebrovascular atherosclerosis are new techniques which await scientific validation before being accepted as standard therapies.
介入神经放射学是一个充满活力的亚专业领域,在神经系统疾病治疗方面正迅速获得新的应用。其最常见的治疗作用仍在于与神经外科支持密切配合,治疗脑动静脉畸形、动脉瘤和瘘管。用血栓形成线圈进行动脉瘤的血管内治疗是一种很有前景的技术,其发病率较低。在所有病例中,尚未实现包括瘤颈在内的动脉瘤完全闭塞的目标,而且该手术尚未显示出比手术夹闭具有明显优势。在一些中心,肿瘤和脊柱病变的术前栓塞是常见的手术。大多数神经外科教学中心都在进行血管成形术和罂粟碱输注以治疗脑血管痉挛。尽管血管造影结果往往令人印象深刻,但相应的临床改善并不总是能看到,尤其是在治疗延迟的情况下。治疗急性中风的溶栓疗法和治疗脑血管动脉粥样硬化的血管成形术是新技术,在被接受为标准疗法之前,尚需科学验证。