Laditan A A
King Fahad Hofuf Hospital, Al-Hassa, Saudi Arabia.
East Afr Med J. 1995 Jun;72(6):376-8.
Cerebrospinal fluid (CSF) was analysed to determine a lumbar puncture (LP) yield for meningitis in 95 children who presented with their first febrile convulsions between July 1993 and June 1994. There were 52 males and 43 females aged six months to six years with a mean age of 21.9 +/- 13.0 months at presentation. 87(91.6%) had simple febrile convulsions (SFC) while the remaining 8(8.4%) had complex febrile convulsions (CFC). The majority of the subjects presented with a sudden onset of convulsions that were preceded by a day or two history of fever, coryza, cough and respiratory distress while others had their convulsions preceded by fever and passage of bloody stools. The LP yield for meningitis in this series was 6.3%. The CSF analysis revealed six cases of meningitis comprising an eight month old infant with Haemophilus influenzae type B (HIB) meningitis, two partially treated pyogenic meningitis and three aseptic meningitis. All of them had presented with febrile convulsions without signs of meningeal irritation. Excluding aseptic meningitis from this series, a 3.1% LP yield for pyogenic meningitis is significant enough to recommend continued performance of LP in children with first febrile convulsions, especially if under the age of eighteen months.
对95名在1993年7月至1994年6月期间首次出现热性惊厥的儿童的脑脊液(CSF)进行分析,以确定腰椎穿刺(LP)诊断脑膜炎的阳性率。其中男性52名,女性43名,年龄在6个月至6岁之间,就诊时平均年龄为21.9±13.0个月。87名(91.6%)为单纯性热性惊厥(SFC),其余8名(8.4%)为复杂性热性惊厥(CFC)。大多数患儿惊厥起病突然,在惊厥发作前有1至2天的发热、鼻炎、咳嗽和呼吸窘迫史,其他患儿则在发热和排血便之后出现惊厥。本系列中LP诊断脑膜炎的阳性率为6.3%。脑脊液分析显示6例脑膜炎,包括1例8个月大的B型流感嗜血杆菌(HIB)脑膜炎患儿、2例部分治疗的化脓性脑膜炎和3例无菌性脑膜炎。所有患儿均表现为热性惊厥,无脑膜刺激征。排除本系列中的无菌性脑膜炎,化脓性脑膜炎的LP阳性率为3.1%,这足以建议对首次热性惊厥的儿童继续进行LP检查,尤其是18个月以下的儿童。