Jahnke K, Maas B, Mödder G
Arch Otorhinolaryngol. 1978 Nov 22;219(2):353-5. doi: 10.1007/BF00463811.
We examined 56 patients with latent or clinically manifest hypothyroidism and 18 patients with acute athyreosis as a control group. We were especially interested in the localization and extent of hearing abnormalities. 45% of the patients with chronic hypothyroidism showed a hearing loss. Of these, two patients had a pure conductive loss, seven a combined hearing loss and 16 a sensori-neural hearing loss. We demonstrated hair cell damage in 13 of the patients with chronic hypothyroidism. The hearing loss was mild to moderate in over 90% of the cases. Although several patients had a basocochlear hearing loss, no characteristic audiogram was found. There was a correlation between the conductive loss and the severity of the hypothyroidism. 50% of the patients showed a significant improvement in hearing after substitution therapy. The results of our examinations are discussed in detail.
我们检查了56例患有潜在性或临床显性甲状腺功能减退症的患者,并将18例急性甲状腺缺失患者作为对照组。我们特别关注听力异常的定位和程度。45%的慢性甲状腺功能减退症患者存在听力损失。其中,2例为单纯传导性听力损失,7例为混合性听力损失,16例为感音神经性听力损失。我们在13例慢性甲状腺功能减退症患者中发现了毛细胞损伤。超过90%的病例中听力损失为轻度至中度。尽管有几位患者存在耳蜗底部听力损失,但未发现特征性听力图。传导性听力损失与甲状腺功能减退症的严重程度之间存在相关性。50%的患者在替代治疗后听力有显著改善。我们详细讨论了检查结果。