Bonetti A, Tirelli F, Arsenio L, Cioni F, Strata A, Zuliani U
Chair of Sports Medicine, University of Parma, Italy.
J Sports Med Phys Fitness. 1995 Jun;35(2):131-5.
Plasma levels of lipoprotein(a), total cholesterol, triglycerides, HDL cholesterol, LDL cholesterol, apoprotein A1 and apoprotein B were assessed in 10 healthy, untrained volunteers subjected to a bicycle ergometric exercise equal to 50% of individual VO2max, followed by increasing loads until muscular exhaustion. Blood samples were taken before the exercise, immediately afterwards and then at 12-hourly intervals for a 72 hours period. Subsequently, the same parameters were evaluated for 8 long-distance runners during the XXIII New York Marathon, with blood samples being taken before and after the race, and then after one month of detraining. After the exercise, lipoprotein(a) in untrained subjects began to decrease significantly from the 24th hour on and remained lower than baseline levels up till the 72nd hour. After detraining, lipoprotein(a) in marathon runners increased significantly both with respect to basal values and especially to post-race values. Modifications of the other metabolic parameters evaluated in both tests were negligible and predictable. In the two groups of subjects examined, no correlation was found between lipoprotein (a) and the anthropometrical data and metabolic parameters considered.
对10名健康的未经训练的志愿者进行了脂蛋白(a)、总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、载脂蛋白A1和载脂蛋白B的血浆水平评估。这些志愿者进行了相当于个体最大摄氧量50%的自行车测力计运动，随后增加负荷直至肌肉力竭。在运动前、运动后立即以及随后72小时内每12小时采集一次血样。随后，在第23届纽约马拉松比赛期间，对8名长跑运动员的相同参数进行了评估，在比赛前后以及停训一个月后采集血样。运动后，未经训练的受试者的脂蛋白(a)从第24小时开始显著下降，直至第72小时一直低于基线水平。停训后，马拉松运动员的脂蛋白(a)相对于基础值，尤其是相对于赛后值显著增加。在两项测试中评估的其他代谢参数的变化可忽略不计且可预测。在两组受试对象中，未发现脂蛋白(a)与所考虑的人体测量数据和代谢参数之间存在相关性。
