Thermann H, Frerichs O, Biewener A, Krettek C, Schandelmeier P
Unfallchirurgische Klinik, Medizinischen Hochschule Hannover.
Unfallchirurg. 1995 Oct;98(10):507-13.
In 84 adult rabbits the biomechanical properties of healing Achilles tendon rupture were examined 2, 4, 8 and 12 weeks (21 each group) after the injury. For the first time a mop-end-tear was performed. The following treatment modalities were applied (7 rabbits in each subgroup): (a) operative functional treatment (resorbable suture; Kleinert techniques); (b) operative functional treatment (fibrin glue); (c) primary functional treatment (conservative). The functional after treatment in all groups was performed with a specially developed orthesis, which was taped to the limb. For biomechanical testing a newly developed fixation technique (cryo-clamp) was applied, which guaranteed secure intratendineal rupture. After 2 weeks the fibrin glue-treated tendon ruptures showed the best results with regard to stiffness, tensile stress and max. rupture force. These results and a higher tensile stress of the sutured tendons were significantly different from those in the conservatively treated groups. After 4 weeks the stiffness in the fibrin group and the energy and rupture force in the suture group were significantly higher than in the group treated conservatively. The 8-week results revealed comparable biomechanical properties. The only significant difference was a higher energy in the fibrin glue group than in the conservative treatment group. The experiment revealed no significant biomechanical differences after 3 months. Compared with the results recorded for plaster immobilization in the literature, the functional treatment resulted in a significantly faster course of healing.
在84只成年兔中,于跟腱断裂损伤后2、4、8和12周(每组21只)检查愈合跟腱的生物力学特性。首次进行了拖把端撕裂。应用了以下治疗方式(每个亚组7只兔):(a)手术功能治疗(可吸收缝线;克莱纳特技术);(b)手术功能治疗(纤维蛋白胶);(c)初始功能治疗(保守治疗)。所有组的功能后续治疗均使用一种专门研制的矫形器,该矫形器用绷带固定在肢体上。为进行生物力学测试,应用了一种新研制的固定技术(冷冻夹),它确保了肌腱内可靠的断裂。2周后,就刚度、拉伸应力和最大断裂力而言,纤维蛋白胶治疗的肌腱断裂显示出最佳结果。这些结果以及缝合肌腱的较高拉伸应力与保守治疗组的结果有显著差异。4周后,纤维蛋白组的刚度以及缝合组的能量和断裂力显著高于保守治疗组。8周的结果显示出相当的生物力学特性。唯一显著的差异是纤维蛋白胶组的能量高于保守治疗组。实验显示3个月后无显著的生物力学差异。与文献中记录的石膏固定结果相比,功能治疗导致愈合过程明显更快。