Martin-Du Pan R C, Goumaz M O, Perrotet C, Burger A
Unité de la thyroïde, Hôpital cantonal, Genève.
Schweiz Med Wochenschr. 1993 Nov 6;123(44):2110-2.
Hypothyroidism followed by hyperthyroidism is described in two patients treated by amiodarone. Euthyroidism was rapidly restored after treatment with antithyroid drugs and potassium perchlorate. The physiopathology of amiodarone-induced hypothyroidism is discussed. Withdrawal of amiodarone is advised in the case of both hypothyroidism and hyperthyroidism.