Lang G E
Augenklinik, Universität Erlangen-Nürnberg.
Klin Monbl Augenheilkd. 1993 Oct;203(4):247-51. doi: 10.1055/s-2008-1045676.
In the literature laser treatment in ischemic central retinal vein occlusion (CRVO) is established to prevent iris neovascularization. We investigated the relationship of morphological and fluorescein angiographic findings with the results of laser treatment.
In 70 (56%) of 125 examined patients with central retinal vein occlusion laser treatment was performed. Indications were either ischemic type of occlusion or macular edema with visual acuity < or = 0.5.
The results compare visual acuity before and after laser treatment (three months and 11.5 months on average) examined by Wilcoxon-test. There was no significant improvement in visual acuity (p = 0.62). After laser treatment 3 (9%) patients with ischemic CRVO developed iris neovascularization and 2 (6%) neovascular glaucoma. There was no correlation between visual outcome and ischemia type (non ischemic type p = 0.61, ischemic type p = 0.67), maculopathy (cystoid macula edema p = 0.87, ischemic maculopathy p = 0.5) and internal diseases (hypertension p = 0.43, diabetes mellitus p = 0.74).
The results of this study indicate that there is no significant visual improvement in patients with CRVO after laser treatment. There are no morphological and angiographic findings indicating a subgroup with good visual prognosis.
在文献中,激光治疗缺血性视网膜中央静脉阻塞(CRVO)已被确立用于预防虹膜新生血管形成。我们研究了形态学和荧光素血管造影结果与激光治疗效果之间的关系。
在125例接受检查的视网膜中央静脉阻塞患者中,70例(56%)接受了激光治疗。治疗指征为缺血性阻塞类型或视力≤0.5的黄斑水肿。
通过Wilcoxon检验比较激光治疗前后(平均3个月和11.5个月)的视力。视力无显著改善(p = 0.62)。激光治疗后,3例(9%)缺血性CRVO患者发生虹膜新生血管形成,2例(6%)发生新生血管性青光眼。视力结果与缺血类型(非缺血型p = 0.61,缺血型p = 0.67)、黄斑病变(黄斑囊样水肿p = 0.87,缺血性黄斑病变p = 0.5)和内科疾病(高血压p = 0.43,糖尿病p = 0.74)之间均无相关性。
本研究结果表明,CRVO患者激光治疗后视力无显著改善。没有形态学和血管造影结果表明存在视力预后良好的亚组。