Clark C R, Lee K E, Ogden J A, McIntosh L S
Yale J Biol Med. 1978 Jul-Aug;51(4):435-40.
Surgical decompression of osteomyelitis in pediatric patients should be an essential part of therapy in most cases. The initial deferral of prompt decompression in two patients because of underlying chronic, hemorrhagic (thrombocytopenic) disorders-one with Wiskott-Aldrich syndrome and one with Gaucher's disease-resulted in more serious and prolonged courses of the infectious processes. The complications might have been ameliorated by earlier drainage in each case. Based upon the experience gained from these two patients, we recommend early drainage, with appropriate treatment of the hemorrhagic disorder, to prevent more widespread dissemination or prolongation of osseous infection in similarly affected children.
在大多数情况下，小儿骨髓炎的手术减压应是治疗的重要组成部分。两名患者因潜在的慢性出血性（血小板减少性）疾病——一名患有维斯科特-奥尔德里奇综合征，另一名患有戈谢病——而最初推迟了及时减压，这导致感染过程更加严重和漫长。在每种情况下，早期引流可能会减轻并发症。基于从这两名患者身上获得的经验，我们建议早期引流，并对出血性疾病进行适当治疗，以防止在类似受影响的儿童中骨感染更广泛地扩散或延长。
