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[干扰素(IFN)在多发性骨髓瘤和非霍奇金淋巴瘤中的应用]

[Interferon (IFN) in multiple myeloma and non-Hodgkin's lymphoma].

作者信息

Gola A

机构信息

Kliniki Hematologii i Chorób Rozrostowych AM we Wrocławiu.

出版信息

Acta Haematol Pol. 1994;25(2 Suppl 1):136-41.

PMID:7520658
Abstract

Interferon combined with cytostatics yielded in multiple myeloma more objective reactions than conventional chemotherapy. Survival time elongation was achieved solely by maintaining myeloma remissions with long term interferon administration. In non-Hodgkin's lymphoma combinations of cytostatics with interferon were more effective than conventional chemo-and radiotherapy only when used in low grade lymphomas of the nodular type. Evidence for longer survival of these patients still waits for presentation.

摘要

与传统化疗相比,干扰素联合细胞抑制剂在多发性骨髓瘤中产生了更多客观反应。仅通过长期给予干扰素维持骨髓瘤缓解才能实现生存时间延长。在非霍奇金淋巴瘤中,细胞抑制剂与干扰素联合仅在用于结节型低级别淋巴瘤时比传统化疗和放疗更有效。这些患者更长生存期的证据仍有待呈现。

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