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[前列腺精囊切除术后复发性前列腺癌中前列腺特异性抗原随访的价值]

[The value of PSA follow-up in recurrent prostate carcinoma after radical prostatovesiculectomy].

作者信息

Trinkler F, Hauri D

机构信息

Urologische Klinik, Universitätsspital Zürich.

出版信息

Helv Chir Acta. 1994 Dec;60(6):1081-5.

PMID:7533147
Abstract

We report our experience in evaluating PSA-follow-up of patients treated with radical prostatectomy. Also PSA is the most sensitive available screening test for relapse after radical prostatectomy, it is not 100% specific for cancer relapse while this serum marker is not specific for prostate cancer. In our opinion, patients with biochemical relapse (PSA > 0.5 ng/l) should undergo an early restaging including biopsy of the anastomosis. In 57% of our patients with PSA > 1.0 ng/l two months after surgery we found clinical recurrence 27 months later on.

摘要

我们报告了我们在评估接受根治性前列腺切除术患者的PSA随访方面的经验。此外,虽然PSA是根治性前列腺切除术后复发最敏感的现有筛查试验,但对于癌症复发它并非100%特异,且这种血清标志物对前列腺癌也不特异。我们认为,生化复发(PSA>0.5 ng/l)的患者应尽早进行重新分期,包括吻合口活检。在我们术后两个月PSA>1.0 ng/l的患者中,57%在27个月后出现了临床复发。

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