Timonen T T, Ilvonen M
Lancet. 1978 Feb 18;1(8060):350-2. doi: 10.1016/s0140-6736(78)91079-6.
45 adults with acute leukaemia or chronic myeloid leukaemia and a control group of patients from the same hospital were asked about the people they had close social contact with before their illness, and about their use of drugs and chemicals. 18 (40%) leukaemia and 6 (13%) control patients had close social contact with hospital personnel or leukaemia patients. 8 (18%) leukaemia patients, but no control patients, had been in close contact with haemotological ward personnel. These differences were statistically significant. 9 (20%) leukaemia and 4 (9%) control patients lived in the same house as healthy persons working in a hospital. No conclusion could be drawn from differences between the two groups in their use of drugs, since the possibility that they were used to treat initial symptoms of leukaemia could not be excluded. Exposure to chemicals, including weed-killers and agricultural insecticides containing a benzene-ring known to be leukaemogenic, was about the same in the two groups.
45名急性白血病或慢性粒细胞白血病患者以及来自同一家医院的一组对照患者被问及他们患病前与之有密切社会接触的人员，以及他们使用药物和化学品的情况。18名（40%）白血病患者和6名（13%）对照患者与医院工作人员或白血病患者有密切社会接触。8名（18%）白血病患者，但无对照患者，曾与血液科病房工作人员密切接触。这些差异具有统计学意义。9名（20%）白血病患者和4名（9%）对照患者与在医院工作的健康人员住在同一所房子里。由于无法排除使用药物是用于治疗白血病初始症状的可能性，因此无法从两组在药物使用方面的差异得出结论。两组接触化学品的情况大致相同，这些化学品包括除草剂和含有已知可致白血病的苯环的农用杀虫剂。
