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对39例因传统血管成形术并发闭塞性夹层而进行的挽救性Palmaz-Schatz冠状动脉支架置入术。

Bailout Palmaz-Schatz coronary stenting in 39 patients with occlusive dissection complicating conventional angioplasty.

作者信息

Antoniucci D, Santoro G M, Bolognese L, Leoncini M, Buonamici P, Fazzini P F

机构信息

Division of Cardiology, Careggi Hospital, Florence, Italy.

出版信息

Cathet Cardiovasc Diagn. 1995 Jul;35(3):204-9. doi: 10.1002/ccd.1810350308.

Abstract

The purpose of this study was to evaluate feasibility, safety, and efficacy of bailout Palmaz-Schatz stenting in a series of 39 patients with coronary dissection associated with acute or unequivocal threatened closure complicating conventional angioplasty. No anatomical characteristics other than reference vessel diameter < 3 mm were considered as contraindications for bailout coronary stenting. Stringent criteria were adopted in defining optimal results (< 10% residual stenosis, no angiographic evidence of residual dissection), suboptimal results (> 10% residual stenosis or angiographic evidence of residual dissection), deployment failure (failure to deploy the stent because of poor trackability or persistent occlusion despite stent deployment). A total of 49 stents and 7 half-stents were implanted in 36 patients (range 1-5; mean 1.45 +/- 0.84). Successful stenting without in-hospital death, urgent or semielective coronary surgery, stent thrombosis, or Q-wave myocardial infarction was achieved in 33/39 patients (85%). A suboptimal result was associated with an increased risk of in-hospital recurrence of ischemia and other related major adverse events (2/5 patients with suboptimal results vs. 1/31 patients with complete deployment success; P < 0.05). Multiple stents implantation did not carry a significant risk of major cardiac adverse events. The results of this study suggest that bailout Palmaz-Schatz stenting may be considered a stand-alone treatment of coronary dissection if an optimal acute angiographic result is achieved.

摘要

本研究的目的是评估39例与急性或明确的有闭塞风险相关的冠状动脉夹层患者在常规血管成形术出现并发症时,使用Palmaz-Schatz支架进行补救性支架置入术的可行性、安全性和有效性。除了参考血管直径<3mm外,没有其他解剖学特征被视为冠状动脉补救性支架置入术的禁忌症。在定义最佳结果(残余狭窄<10%,无残余夹层的血管造影证据)、次优结果(残余狭窄>10%或有残余夹层的血管造影证据)、置入失败(由于跟踪性差或尽管置入支架仍持续闭塞而未能成功置入支架)时采用了严格的标准。36例患者共植入49个支架和7个半支架(范围1 - 5个;平均1.45±0.84个)。33/39例患者(85%)成功置入支架,且无院内死亡、紧急或半择期冠状动脉手术、支架血栓形成或Q波心肌梗死。次优结果与院内缺血复发及其他相关主要不良事件的风险增加相关(5例次优结果患者中有2例,完全成功置入支架的31例患者中有1例;P<0.05)。多次支架置入并未带来显著的主要心脏不良事件风险。本研究结果表明,如果能获得最佳的急性血管造影结果,Palmaz-Schatz支架补救性置入术可被视为冠状动脉夹层的独立治疗方法。

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