吸入暴露期间实验动物体温的连续监测。

Continuous monitoring of temperature in laboratory animals during inhalation exposure.

作者信息

Laham S, Schrader K, Symonds G, Curtin W

出版信息

Drug Chem Toxicol. 1978;1(3):237-50. doi: 10.3109/01480547809105018.

Abstract

An automatic system was developed to monitor continuously the colonic temperature of laboratory animals during inhalation exposure to toxic chemicals. It includes: an automatic switchbox, a control circuit, a recorder and a digital voltmeter. The system was calibrated for different temperature ranges and used for a year to assess the effects of household solvents on temperature of Sprague-Dawley rats. Reliable monitoring of temperature in 16 rats was carried out in a sequential manner in the manual mode or in the automatic mode for several consecutive days. Very slight changes (.01 - .02 degrees C) in temperature can be measured with this system.

摘要

开发了一种自动系统，用于在实验动物吸入有毒化学物质期间持续监测其结肠温度。该系统包括：一个自动配电箱、一个控制电路、一台记录仪和一个数字电压表。该系统针对不同温度范围进行了校准，并使用了一年来评估家用溶剂对斯普拉格-道利大鼠体温的影响。在手动模式或自动模式下，连续数天以顺序方式对16只大鼠的体温进行了可靠监测。使用该系统可以测量出非常微小的温度变化（0.01 - 0.02摄氏度）。