Favilli S, De Simone L, Scarano E, Repetto T, Manetti A
U.O. Cardiologia Osp. A. Meyer, USL, Firenze.
G Ital Cardiol. 1995 Jul;25(7):885-90.
Congenital arteriovenous malformations represent a rare cause of heart failure in neonates.
Four neonates with arteriovenous malformations (cerebral in one, hepatic in two and pulmonary in one) are reported.
In the first three cases Color Doppler echography was able to image the arteriovenous malformations, to identify the afferent and efferent vessels and to quantify the arteriovenous shunt. In the neonate with pulmonary malformation, a cardiac cause of heart failure was excluded by echocardiography, and the diagnosis was stated by selective angiography. The neonate with cerebral great arteriovenous malformation died at 4th day of life. The two neonates with hepatic malformations improved both with medical therapy; in the last neonate, with multiple arteriovenous pulmonary fistulae, selective embolization was performed, but the child died a few months later.
Congenital arteriovenous malformations are rare, and an early diagnosis is the base for a correct therapy; Color Doppler echography represents the gold standard for cerebral and hepatic malformations, while selective angiography should be reserved to patients who might profit of embolization or surgical resection.
先天性动静脉畸形是新生儿心力衰竭的罕见病因。
报告了4例患有动静脉畸形的新生儿(1例为脑动静脉畸形,2例为肝动静脉畸形,1例为肺动静脉畸形)。
在前3例病例中,彩色多普勒超声能够对动静脉畸形进行成像,识别输入和输出血管,并对动静脉分流进行量化。在患有肺畸形的新生儿中,超声心动图排除了心力衰竭的心脏病因,并通过选择性血管造影做出诊断。患有脑巨大动静脉畸形的新生儿在出生后第4天死亡。2例患有肝畸形的新生儿经药物治疗后均有改善;在最后1例患有多发性肺动静脉瘘的新生儿中,进行了选择性栓塞,但患儿在几个月后死亡。
先天性动静脉畸形罕见,早期诊断是正确治疗的基础;彩色多普勒超声是脑和肝畸形的金标准,而选择性血管造影应仅用于可能从栓塞或手术切除中获益的患者。