Gajda M, Tyloch F, Jóźwicki W, Tyloch J, Sujkowska R, Skok Z
Department of Clinical Pathomorphology, Medical Academy, Bydgoszcz, Poland.
Int J Occup Med Environ Health. 1995;8(2):103-8.
In the retrospective investigation we estimated the CEA levels in urine and urine cytology in 293 patients with urinary bladder cancer (group I) and in 129 patients with urinary tract infection (group II). An increased CEA level was found in 212 cases of bladder cancer and in 109 cases of urinary infection. Neoplastic cells in urine sediment were identified in 254 cases in the first group, while in the second, multiple inflammatory cells and pyuria were diagnosed in 55 and 56 cases, respectively. The combined examination (increased CEA level and/or positive cytology of the urine sediment) allowed for the diagnosis of neoplastic disease in 270 patients in the first group and infection diseases in 123 patients in the second group. After surgical therapy an increased urine CEA level and neoplastic cells in the urine cytology were found in 1 case which was then confirmed histopathologically. In the group with urinary infection an increased CEA level in urine, after antiphlogistic therapy, was found in 5 cases, inflammatory cells in 12 cases, pyuria in 8 cases and suspect cells were found in 6 cases in the group with urinary infection. In specimens from these cases, after electroresection, bladder cancer was diagnosed in 2, and cystitis cystica type changes in 2 cases.
在这项回顾性研究中，我们对293例膀胱癌患者（第一组）和129例尿路感染患者（第二组）的尿液癌胚抗原（CEA）水平及尿细胞学进行了评估。在212例膀胱癌患者和109例尿路感染患者中发现CEA水平升高。第一组254例患者尿沉渣中发现肿瘤细胞，而第二组分别有55例和56例诊断为多个炎性细胞及脓尿。联合检查（CEA水平升高和/或尿沉渣细胞学阳性）使第一组270例患者诊断为肿瘤性疾病，第二组123例患者诊断为感染性疾病。手术治疗后，1例患者尿CEA水平升高且尿细胞学发现肿瘤细胞，随后经组织病理学证实。在尿路感染组，抗炎治疗后，5例患者尿CEA水平升高，12例有炎性细胞，8例有脓尿，6例发现可疑细胞。在这些病例的标本经电切术后，2例诊断为膀胱癌，2例诊断为囊性膀胱炎样改变。
