Mbugua G G, Muthami L N, Mutura C W, Oogo S A, Waiyaki P G, Lindan C P, Hearst N
Kenya Medical Research Institute, Nairobi, Kenya.
East Afr Med J. 1995 Aug;72(8):515-8.
A total number of two hundred eighty three long distance truck drivers and their assistants (loaders) who ferry goods between Kenya and Zaire were included in a cross-sectional study between September 1991 and April 1992. Twenty six percent of the study subjects were seropositive for HIV-1 and none were HIV-2 seropositive. Countries of birth and residence were significantly associated with HIV infection (X2 = 23.6, P = 0.0006). Significant associations were also found between HIV seropositivity and level of education from secondary school and above (OR = 3.4, 95% C.I. = 1.01-11.55); being circumcised was more protective, (OR = 0.38; 95% C.I. = 0.19-0.76), history of many years of driving (X2 = 9.3, p = 0.0254) and income (OR = 11.13, 95% C.I. = 1.35-91.95). When a stepwise multiple logistic regression model was fitted to all the variables observed to be significant in the univariate analysis, the following risk factors attained statistical significance: lack of circumcision (OR = 3.75); income greater than Ksh. 2000 (OR = 7.24); being employed in long distance driving more than 11 years (OR = 3.98); and secondary school education and above (OR = 4.06, 95% C.I. = 1.18-13.98). Reference for all the above Odds Ratios was 1.
1991年9月至1992年4月期间,一项横断面研究纳入了总共283名在肯尼亚和扎伊尔之间运输货物的长途卡车司机及其助手(装卸工)。26%的研究对象HIV-1血清学检测呈阳性,无一例HIV-2血清学检测呈阳性。出生国和居住国与HIV感染显著相关(X2 = 23.6,P = 0.0006)。在HIV血清学阳性与中学及以上教育水平之间也发现了显著关联(OR = 3.4,95%置信区间 = 1.01 - 11.55);接受包皮环切术的保护作用更强(OR = 0.38;95%置信区间 = 0.19 - 0.76),多年驾驶史(X2 = 9.3,p = 0.0254)和收入(OR = 11.13,95%置信区间 = 1.35 - 91.95)。当对单因素分析中观察到的所有显著变量拟合逐步多元逻辑回归模型时,以下危险因素具有统计学意义:未接受包皮环切术(OR = 3.75);收入高于2000肯尼亚先令(OR = 7.24);从事长途驾驶超过11年(OR = 3.98);中学及以上教育水平(OR = 4.06,95%置信区间 = 1.18 - 13.98)。上述所有比值比的参照值为1。