Lasa M S, Datiles M B, Magno B V, Mahurkar A
Ophthalmic Genetics Branch, National Eye Institute, National Institutes of Health, Bethesda, MD 20892-1860, USA.
Ophthalmic Surg. 1995 Mar-Apr;26(2):110-3.
We describe a method to objectively document postcataract surgery posterior capsule opacification using Zeiss Scheimpflug photography and computerized image analysis. We examined 42 eyes with clear capsules (group A) and 27 with posterior capsule opacities (group B). The group A eyes had significantly better visual acuity (P < .05), lower mean capsular densitometry readings (0.03 +/- 0.03 optical density units versus 0.15 +/- 0.11 optical density units; P < .0001), and thinner capsules (0.03 +/- 0.4 mm versus 0.10 +/- 0.05 mm) than the group B eyes. This new objective method of documenting postoperative capsular haze may be useful for clinical studies such as clinical trials of drugs or surgical techniques being developed to prevent or minimize capsule opacification.
我们描述了一种使用蔡司Scheimpflug摄影技术和计算机图像分析客观记录白内障手术后后囊膜混浊的方法。我们检查了42只囊膜清晰的眼睛(A组)和27只有后囊膜混浊的眼睛(B组)。A组眼睛的视力明显更好(P <.05),平均囊膜密度测量读数更低(0.03±0.03光密度单位对0.15±0.11光密度单位;P <.0001),并且囊膜比B组眼睛更薄(0.03±0.4毫米对0.10±0.05毫米)。这种记录术后囊膜混浊的新客观方法可能对临床研究有用,例如正在开发的预防或最小化囊膜混浊的药物或手术技术的临床试验。