Saunders J E, Luxford W M, Devgan K K, Fetterman B L
House Ear Clinic, Los Angeles, CA 90059, USA.
Otolaryngol Head Neck Surg. 1995 Jul;113(1):23-31. doi: 10.1016/S0194-59989570140-0.
Patients with acoustic neuroma may have sudden sensorineural hearing loss. Most patients with sudden hearing loss seek medical attention promptly, but the diagnosis of an acoustic neuroma may be delayed for months or years because sudden hearing loss is an unusual initial symptom of an acoustic neuroma. In a retrospective review of 836 cases of sudden hearing loss, we found 13 patients with acoustic neuromas. The prevalence of acoustic neuromas for those screened with auditory brain stem response or magnetic resonance imaging was 2.5%. In addition to these 13 patients, 79 acoustic neuroma patients treated in our clinic had well-documented sudden hearing loss as the initial symptom. Hearing loss in these 92 patients ranged from mild to profound. Associated symptoms of pain, facial paresthesia, or unilateral tinnitus preceding the sudden hearing loss were suggestive of an acoustic neuroma, as was a midfrequency (U-shaped) hearing loss. A history of other diseases or events that might explain the sudden hearing loss, a normal electronystagmogram, or recovery of hearing does not eliminate the possibility of a tumor. Because there are no clinical findings that clearly distinguish those patients with acoustic neuromas from other patients with sudden hearing loss, we recommend either an evaluation with auditory brain stem response or gadolinium-enhanced magnetic resonance imaging for any patient with sudden hearing loss.
听神经瘤患者可能会突然出现感音神经性听力损失。大多数突发听力损失的患者会迅速就医,但听神经瘤的诊断可能会延迟数月或数年,因为突发听力损失是听神经瘤不常见的初始症状。在一项对836例突发听力损失病例的回顾性研究中,我们发现了13例听神经瘤患者。经听觉脑干反应或磁共振成像筛查的患者中听神经瘤的患病率为2.5%。除了这13例患者外,我们诊所治疗的79例听神经瘤患者也有明确记录的以突发听力损失为初始症状。这92例患者的听力损失程度从轻度到重度不等。突发听力损失之前出现的疼痛、面部感觉异常或单侧耳鸣等相关症状提示听神经瘤,中频(U形)听力损失也是如此。有其他可能解释突发听力损失的疾病或事件史、眼震电图正常或听力恢复并不能排除肿瘤的可能性。由于没有临床发现能明确区分听神经瘤患者与其他突发听力损失患者,我们建议对任何突发听力损失的患者进行听觉脑干反应评估或钆增强磁共振成像检查。