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镁在孕期中的作用。

Role of magnesium in pregnancy.

作者信息

Zarcone R, Cardone G, Bellini P

机构信息

2nd Department of Institute of Gynecology and Obstetrics, Second University of Naples, Italy.

出版信息

Panminerva Med. 1994 Dec;36(4):168-70.

PMID:7603732
Abstract

The importance of magnesium in pregnancy has been emphasised by several studies. Magnesium is considered a membrane-stabilizing ion and a permeability regulator acting at an intracellular level which intervenes in the oxidative phosphorylation and oxidation reduction processes as well as in enzymatic synthesis and activity. The authors performed a double-blind study in which 15 mmol of magnesium or placebo were administered to the treatment and control groups respectively. There were more cases admitted to hospital in the control group than in that treated with magnesium. Even if there is not a large body of data which supports improved fetus development as a result of magnesium supplementation during pregnancy, the authors suggest that pregnant women with a high risk of gestosis and premature labour should receive additional magnesium.

摘要

多项研究强调了镁在孕期的重要性。镁被认为是一种膜稳定离子和通透性调节剂,在细胞内发挥作用,参与氧化磷酸化和氧化还原过程以及酶的合成与活性。作者进行了一项双盲研究,分别给治疗组和对照组给予15毫摩尔的镁或安慰剂。对照组入院的病例比镁治疗组更多。即使没有大量数据支持孕期补充镁能改善胎儿发育,但作者建议,有妊娠中毒症和早产高风险的孕妇应额外补充镁。

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