Nishioka S de A
Biomedical Sciences Center, Uberlândia Federal University, MG.
Sao Paulo Med J. 1994 Apr-Jun;112(2):561-3. doi: 10.1590/s1516-31801994000200008.
Two cases of parenteral injection of organophosphate insecticide are reported. A 20-year-old man injected himself malathion intramuscularly. The developed necrosis in the injection set and abscess formation, and developed a severe poisoning reaction of late onset that was fully manifested 60 hours after the injection. A 22-year-old girl injected herself subcutaneously a small amount of fenitrothion and had severe swelling of the affected limb and a sterile abscess. In cases of parenteral injection of organophosphates, attention must be paid to the possibility of late onset of the clinical manifestations of the poisoning, and to the fact that usual measures to reduce exposure to the organophosphate, such as induction of vomiting, gastric lavage and use of activated charcoal are probably ineffective. Local complications at the site of the injection, like necrosis and abscesses are also expected findings.
报告了两例经肠胃外注射有机磷杀虫剂的病例。一名20岁男性给自己肌肉注射了马拉硫磷。注射部位出现坏死并形成脓肿，且出现了迟发性严重中毒反应，在注射60小时后完全显现出来。一名22岁女孩给自己皮下注射了少量杀螟硫磷，患侧肢体出现严重肿胀和无菌性脓肿。在经肠胃外注射有机磷的病例中，必须注意中毒临床表现迟发的可能性，以及常规减少有机磷暴露的措施，如催吐、洗胃和使用活性炭可能无效这一事实。注射部位的局部并发症，如坏死和脓肿也是预期会出现的情况。
