Hess T, Gleitz M, Hanser U, Mittelmeier H, Kubale R
Orthopädische Universitäts- und Poliklinik Homburg/Saar.
Z Orthop Ihre Grenzgeb. 1995 May-Jun;133(3):222-6. doi: 10.1055/s-2008-1039441.
In this study, we tested the stability of the xenograft SURGIBONE and of human iliac crest graft depending on the donor's bone density. The mean load bearing capacity of SURGIBONE was 4816 N, the compressive strength 32.8 N/mm2. This even exceeds the values given by the producer. Yet in clinical use the material caused problems by collapses or lysis of the graft. According to our results, those failures can not be explained by missing primary stability. Perhaps there is a immunogenic reaction of the host against the remaining protein as it once was proved for the "kielspan"-graft. The iliac crest grafts of donors with normal bone density had a load bearing capacity of 3397 N. Grafts of donors with reduced bone density of less than 60 mg/ml Ca-Equivalent showed reduced load bearing capacities of 2265 N. DEXA (Dual-Energy X-Ray Absorptiometry) seems to be suitable to scan preoperatively the iliac crest graft stability in order to recognize the danger of reduced stability by osteoporosis.
在本研究中,我们根据供体骨密度测试了异种移植骨SURGIBONE和人髂嵴骨移植的稳定性。SURGIBONE的平均承载能力为4816 N,抗压强度为32.8 N/mm²。这甚至超过了生产商给出的值。然而在临床应用中,该材料因移植骨塌陷或溶解而出现问题。根据我们的结果,这些失败不能用缺乏初始稳定性来解释。也许宿主对残留蛋白质存在免疫反应,就像“基尔斯潘”移植骨曾被证实的那样。骨密度正常的供体的髂嵴骨移植承载能力为3397 N。钙当量低于60 mg/ml的骨密度降低的供体的移植骨承载能力降低至2265 N。双能X线吸收法(DEXA)似乎适合术前扫描髂嵴骨移植的稳定性,以识别因骨质疏松导致稳定性降低的风险。