Hoffman J I
Department of Pediatrics, University of California-San Francisco 94143, USA.
Pediatr Cardiol. 1995 May-Jun;16(3):103-13. doi: 10.1007/BF00801907.
The incidence of congenital heart disease (CHD) in the Western industrialized world has varied from a low value of about 3 to 5 per 1000 live births to about 12 per 1000 live births. Most of the lower incidence figures were obtained before there were sufficiently well trained pediatric cardiologists and before the success of cardiac surgery put a premium on early and correct diagnosis of CHD. The advent of echocardiography with Doppler color flow measurements has made it possible to diagnose lesions that are asymptomatic, minor, and even without murmurs. Given these differences, there does not appear to have been a significant increase in the incidence of CHD over the last 20-30 years. The incidence of CHD in underdeveloped countries is not known, but the distribution of different lesions is fairly similar to those in developed countries except perhaps for fewer with aortic stenosis and coarctation of the aorta.
在西方工业化国家,先天性心脏病(CHD)的发病率有所不同,每1000例活产儿中,发病率低时约为3至5例,高时约为12例。大多数较低的发病率数据是在没有足够训练有素的儿科心脏病专家之前,以及在心脏手术成功使得早期和正确诊断CHD变得至关重要之前获得的。超声心动图与多普勒彩色血流测量技术的出现,使得诊断无症状、轻微甚至无杂音的病变成为可能。鉴于这些差异,在过去20至30年里,CHD的发病率似乎并未显著增加。欠发达国家CHD的发病率尚不清楚,但除了主动脉瓣狭窄和主动脉缩窄的病例可能较少外,不同病变的分布与发达国家相当相似。