Andersson G
Department of Physiology and Biophysics, University of Lund, Sweden.
Acta Physiol Scand. 1995 Apr;153(4):381-92. doi: 10.1111/j.1748-1716.1995.tb09876.x.
In pentobarbitone-anaesthetized cats, responses were recorded as surface positive potentials in the motor cortex on forelimb and brachium conjunctivum stimulation. In such a preparation, the forelimb nerve responses are mediated via the spino-cervical tract and the dorsal column-lemniscal pathway. Lesions of the sensory cortex (sparing only the depth of the coronary sulcus) abolished or reduced short-latency peripheral responses, in the motor cortex, on both skin and muscle nerve stimulation to less than 10% of control, while brachium conjunctivum responses were unchanged. Lesions of the second somatosensory area alone reduced the motor cortex responses on peripheral nerve stimulation by 10-20%. When the sensory cortex was inactivated by spreading depression, peripheral responses in the motor cortex were abolished before the spreading depression reached the recording point, as judged from the brachium conjunctivum response. The depth distribution of positive and negative field potentials, constituting the early components of a peripheral response in the motor cortex, closely resembled that of a cortico-cortical response evoked on stimulation in area 3. It differed from that of thalamo-cortical response evoked on brachium conjunctivum stimulation. These data suggest that most, if not all, sensory input through the dorsal column and spino-cervical tract to the motor cortex is mediated via the sensory cortex.
在戊巴比妥麻醉的猫中，在前肢和结合臂刺激时，运动皮层的反应被记录为表面正电位。在这样的准备状态下，前肢神经反应通过脊髓颈髓束和背柱-薄束通路介导。感觉皮层损伤（仅保留冠状沟深度）使运动皮层对皮肤和肌肉神经刺激的短潜伏期外周反应消失或减少至对照的不到10%，而结合臂反应未改变。单独损伤第二体感区使运动皮层对外周神经刺激的反应降低10%-20%。当感觉皮层因扩散性抑制而失活时，根据结合臂反应判断，在扩散性抑制到达记录点之前，运动皮层的外周反应就已消失。构成运动皮层外周反应早期成分的正负场电位的深度分布，与在3区刺激诱发的皮质-皮质反应的深度分布非常相似。它与结合臂刺激诱发的丘脑-皮质反应的深度分布不同。这些数据表明，通过背柱和脊髓颈髓束到运动皮层的大部分（如果不是全部）感觉输入是通过感觉皮层介导的。
