Brussaard J H, Hulshof K F, Löwik M R
Department of Human Nutrition, TNO Nutrition and Food Research, Zeist, The Netherlands.
Ann Nutr Metab. 1995;39(2):85-94. doi: 10.1159/000177847.
To estimate the effect of possible goitre prophylactic measures on the intake of iodine among population groups, simulation studies, based on the first Dutch National Food Consumption Survey, were carried out. Iodine intake figures and prevalence of low intakes were calculated after fictively iodizing either bread, a combination of industrial products, milk and dairy products (without cheese) or margarine and shortenings. In addition, the effect of iodizing both bread and cheese or bread + biscuits + rusks was calculated. The simulated iodization of different products increased mean calculated iodine intakes by up to 45% and gave a reduction of 60-90% in the prevalence of iodine intakes below 100 micrograms/day. The maximum acceptable intake of 1 mg iodine per day was never reached by any subject (average of 2 days). It is concluded that it is possible to increase substantially the mean iodine intake of the Dutch population and to decrease the prevalence of low iodine intakes without a clear risk of exceeding the maximum acceptable daily oral iodine intake.
为评估可能的甲状腺肿预防措施对不同人群碘摄入量的影响,基于荷兰首次全国食品消费调查开展了模拟研究。在虚拟地对面包、工业产品组合、牛奶及奶制品(不含奶酪)或人造黄油和起酥油进行碘化处理后,计算碘摄入量数据及低摄入量的患病率。此外,还计算了对面包和奶酪或面包+饼干+脆饼进行碘化处理的效果。不同产品的模拟碘化处理使计算出的平均碘摄入量最多增加了45%,并使碘摄入量低于100微克/天的患病率降低了60%至90%。任何受试者在任何一天(平均2天)都未达到每日1毫克碘的最大可接受摄入量。得出的结论是,在没有明显超过每日口服碘最大可接受摄入量风险的情况下,大幅提高荷兰人群的平均碘摄入量并降低低碘摄入量的患病率是可能的。