Oates E, Austin J M, Becker J L
Department of Radiology, New England Medical Center, Boston, Massachusetts 02111, USA.
J Nucl Med. 1995 Aug;36(8):1368-71.
For the evaluation of a variety of hepatosplenic disorders, SPECT complements planar 99mTc-sulfur colloid liver/spleen imaging. By isolating small, ectopic or poorly functioning spleen(s) from overlying or adjacent liver, SPECT imaging should facilitate identification of splenic tissue in infants with suspected heterotaxy syndrome.
During a 10-yr period, 10 planar-only and 9 planar-plus-SPECT liver/spleen scans were obtained from 15 infants, 13 of whom were less than 1 mo of age at first examination. Four of the planar-only group had follow-up planar-plus-SPECT imaging. Scintigraphic diagnosis regarding presence of splenic tissue was correlated with clinical diagnosis.
Thirteen infants had splenic tissue; two were asplenic. Planar-only imaging provided correct diagnoses in six [four with, two without spleen(s)] but was negative or equivocal in four infants. Planar-plus-SPECT imaging was positive in all in whom it was performed; moreover, in 4/13 infants (31%), splenic tissue was documented only by SPECT imaging.
Particularly when planar views are inconclusive, SPECT imaging is invaluable for identification and localization of functioning splenic tissue in infants with suspected heterotaxy syndrome.
为评估多种肝脾疾病，单光子发射计算机断层扫描（SPECT）可补充平面99m锝-硫胶体肝/脾显像。通过将小的、异位的或功能不良的脾脏与覆盖其上或相邻的肝脏区分开，SPECT显像应有助于识别疑似内脏反位综合征婴儿的脾组织。
在10年期间，从15名婴儿中获得了10次仅平面显像和9次平面加SPECT的肝/脾扫描，其中13名婴儿在首次检查时年龄小于1个月。仅平面显像组中有4名婴儿进行了后续的平面加SPECT显像。关于脾组织存在的闪烁显像诊断与临床诊断相关。
13名婴儿有脾组织；2名无脾。仅平面显像在6名婴儿中做出了正确诊断（4名有脾，2名无脾），但在4名婴儿中结果为阴性或不明确。平面加SPECT显像在所有进行该检查的婴儿中均为阳性；此外，在13名婴儿中有4名（31%），仅通过SPECT显像记录到了脾组织。
特别是当平面显像结果不明确时，SPECT显像对于识别和定位疑似内脏反位综合征婴儿的功能性脾组织非常有价值。
