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[奥狄括约肌高血压性运动障碍的管理。内镜括约肌切开术并发症发生率与胆总管直径之间的相关性]

[Management of hypertensive dyskinesia of Oddi's sphincter. Correlation between the frequency of complications from endoscopic sphincterotomy and the diameter of the common bile duct].

作者信息

Simon L, Döbrönte Z, Patai A

机构信息

Tolna Megyei Onkormányzat Kórháza Gastroenterologiai Osztály.

出版信息

Orv Hetil. 1995 Jul 30;136(31):1659-62.

PMID:7637986
Abstract

OBJECTIVES

to evaluate the treatment possibilities in different forms of sphincter of Oddi dysfunction (SOD), in particularly that of the hypertonic sphincter of Oddi dyskinesia (HOD, biliary type group III). In the first part of retrospective evaluation the higher complication rate of endoscopic sphincterotomy (EST) and its probable causes were analysed.

MATERIAL AND METHODS

The frequency and reasons of post-EST complications were retrospectively evaluated in a three-year (1990-1992) EST material of two gastroenterological departments using identical treatment principles and methods. Endoscopic sphincterotomies performed for bile duct stone extraction or treatment of HOD in cholecystectomized patients were included only. The data of 308 patients were analysed regarding two areas: 1. EST was performed for HOD treatment in 20 patients, and in 288 patients for stone removal, 2. the diameter of common bile duct was found non-dilated in 40 patients, and dilated in 268 patients, respectively.

RESULTS

  1. The frequency of complications in the group of patients with EST for HOD treatment was significantly higher: 8/20 (40%) vs. 17/288 (5.9%) (p < 0.01). 2. There was also a significant difference in the percentage of total complications between the patients of nondilated bile ducts and those patients with dilated bile ducts: 8/268 (3.3%) vs. 17/40 (42.50%) (p < 0.01), detailed: bleeding: 4/268 vs. 6/40, pancreatitis: 4/268 vs. 10/40, and perforation: 0 vs. 1/40.

CONCLUSIONS

Therapeutic endoscopic sphincterotomy is more hazardous in patients with non-dilated bile ducts, thus evidently also in patients suffering from the biliary III. type (hypertonic Oddi-sphincter dyskinesia) of sphincter of Oddi dysfunctions.

摘要

目的

评估不同形式的Oddi括约肌功能障碍(SOD),尤其是高张性Oddi括约肌运动障碍(HOD,胆管型III组)的治疗可能性。在回顾性评估的第一部分中,分析了内镜括约肌切开术(EST)较高的并发症发生率及其可能原因。

材料与方法

回顾性评估两个胃肠病科在三年(1990 - 1992年)内采用相同治疗原则和方法的EST病例资料中EST术后并发症的发生频率及原因。仅纳入为胆囊切除术后患者进行胆管结石取出或HOD治疗而实施的内镜括约肌切开术。分析了308例患者在两个方面的数据:1. 20例患者因HOD治疗而行EST,288例患者因结石取出而行EST;2. 胆总管直径未扩张的患者有40例,扩张的患者有268例。

结果

  1. 因HOD治疗而行EST的患者组并发症发生率显著更高:8/20(40%)对比17/288(5.9%)(p < 0.01)。2. 胆总管未扩张患者与扩张患者的总并发症百分比也存在显著差异:8/268(3.3%)对比17/40(42.50%)(p < 0.01),具体为:出血:4/268对比6/40,胰腺炎:4/268对比10/40,穿孔:0对比1/40。

结论

治疗性内镜括约肌切开术在胆总管未扩张的患者中风险更高,因此在Oddi括约肌功能障碍的胆管III型(高张性Oddi括约肌运动障碍)患者中显然也是如此。

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