Screening for Barrett's esophagus by balloon cytology.

OBJECTIVE

to determine whether balloon cytology would allow a nonendoscopic diagnosis of Barrett's esophagus.

METHODS

In 10 unselected patients with Barrett's esophagus, balloon cytology was performed with a Brandt esophageal cytology balloon catheter prior to endoscopy/esophageal biopsy. Specimens were cytologically evaluated for the presence of goblet cells and/or dysplasia.

RESULTS

No patient had goblet cells or definitive columnar cell dysplasia.

CONCLUSION

This technique with a commercially available balloon catheter does not allow for a nonendoscopic diagnosis of Barrett's esophagus.