POEMS综合征

POEMS syndrome.

作者信息

Perniciaro C

机构信息

Department of Dermatology, Mayo Clinic Jacksonville, FL 32224, USA.

出版信息

Semin Dermatol. 1995 Jun;14(2):162-5. doi: 10.1016/s1085-5629(05)80013-6.

DOI:10.1016/s1085-5629(05)80013-6

PMID:7640197

Abstract

The principal features of POEMS syndrome are osteosclerotic bone lesions, peripheral sensorimotor neuropathy, and elevated levels of a monoclonal protein in the serum or urine. Skin lesions are present in the majority of patients with POEMS syndrome. Diffuse hyperpigmentation is the most common cutaneous finding. Hemangiomas with histopathological features resembling renal glomeruli are the most specific skin lesions.

摘要

POEMS综合征的主要特征为骨硬化性骨病变、周围感觉运动神经病，以及血清或尿液中单克隆蛋白水平升高。大多数POEMS综合征患者存在皮肤病变。弥漫性色素沉着是最常见的皮肤表现。具有类似于肾小球组织病理学特征的血管瘤是最具特异性的皮肤病变。