Ding G X, Rogers D W, Mackie T R
Institute for National Measurement Standards, National Research Council of Canada, Ottawa.
Med Phys. 1995 May;22(5):489-501. doi: 10.1118/1.597581.
The Spencer-Attix water/air restricted mass collision stopping-power ratio is calculated in realistic electron beams in the energy range from 5-50 MeV for a variety of clinical accelerators including the Varian Clinac 2100C, the Philips SL75-20, the Siemens KD2, the AECL Therac 20, and the Scanditronix Medical Microtron 50. The realistic clinical beams are obtained from full Monte Carlo simulations of the clinical linear accelerators using the code BEAM. The stopping-power ratios calculated using clinical beams are compared with those determined according to the AAPM and the IAEA protocols which were calculated by using monoenergetic parallel beams. Using the energy-range relationship of Rogers and Bielajew [Med. Phys. 13, 687-694 (1986)] leads to the most consistent picture in which the stopping-power ratios at dmax derived from mono-energetic calculations underestimate the stopping-power ratios calculated with the realistic beam by 0.3% at 5 MeV and up to 1.4% at 20 MeV. The stopping-power ratios at dmax determined according to the AAPM TG-21 protocol (1983) are shown to overestimate the realistic stopping-power ratios by up to 0.6% for a 5-MeV beam and underestimate them by up to 1.2% for a 20-MeV beam. Those determined according to the IAEA (1987) protocol overestimate the realistic stopping-power ratios by up to 0.3% for a 5-MeV beam and underestimate them by up to a 1.1% for a 20-MeV beam at reference depth. The causes of the differences in the stopping-power ratios between the realistic clinical mono-energetic beams are analyzed quantitatively. The changes in the stopping-power ratios at dmax are mainly due to the energy spread of the electron beam and the contaminant photons in the clinical beams. The effect of the angular spread of electrons is rather small except at the surface. Data are presented which give the corrected stopping-power ratios at dmax or reference depth starting from those determined according to protocols for any energy of clinical electron beams with scattering foils. For scanned clinical electron beams the correction to stopping-power ratios determined according to protocols is found to be less than 0.5% at dmax or reference depth for all beam energies studied. We quantify the differences in the stopping-power ratios determined using the depth of 50% ionization level and the depth of 50% dose level. The differences are very small except for very-high-energy beams (50 MeV) where they can be up to 0.8%.
在能量范围为5 - 50 MeV的实际电子束中,针对多种临床加速器(包括瓦里安Clinac 2100C、飞利浦SL75 - 20、西门子KD2、加拿大原子能公司Therac 20以及斯堪的亚医疗微型加速器50),计算了斯宾塞 - 阿蒂克斯水/空气受限质量碰撞阻止本领比。实际临床束流是使用BEAM程序对临床直线加速器进行全蒙特卡罗模拟得到的。将使用临床束流计算得到的阻止本领比与根据美国医学物理学会(AAPM)和国际原子能机构(IAEA)协议使用单能平行束流计算得到的结果进行比较。利用罗杰斯和别拉耶夫[《医学物理》13, 687 - 694 (1986)]的能量范围关系,得到了最一致的情况,即从单能计算得出的dmax处的阻止本领比低估了用实际束流计算得到的阻止本领比,在5 MeV时低估0.3%,在20 MeV时高达1.4%。根据AAPM TG - 21协议(1983)确定的dmax处的阻止本领比,对于5 MeV的束流高估实际阻止本领比高达0.6%,对于20 MeV的束流低估高达1.2%。根据IAEA(1987)协议确定的结果,对于5 MeV的束流在参考深度高估实际阻止本领比高达0.3%,对于20 MeV的束流低估高达1.1%。对实际临床单能束流之间阻止本领比差异的原因进行了定量分析。dmax处阻止本领比的变化主要归因于电子束的能量展宽和临床束流中的污染光子。除了在表面处,电子角展宽的影响相当小。给出了从根据带有散射箔的临床电子束任何能量的协议确定的结果开始,在dmax或参考深度处的校正阻止本领比数据。对于扫描临床电子束,发现在dmax或参考深度处,根据协议确定的阻止本领比的校正对于所有研究的束流能量都小于0.5%。我们对使用50%电离水平深度和50%剂量水平深度确定的阻止本领比的差异进行了量化。除了非常高能量的束流(50 MeV),差异非常小,在50 MeV时差异可达0.8%。