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[苄达酸肝毒性:16例病例分析]

[Bendazac hepatotoxicity: analysis of 16 cases].

作者信息

Prieto de Paula J M, Rodríguez Rodríguez E, Villamandos Nicás V, Sanz de la Fuente H, Prada Mínguez A, del Portillo Rubí A

机构信息

Servicio de Medicina Interna, Hospital Santos Reyes, Aranda de Duero, Burgos.

出版信息

Rev Clin Esp. 1995 Jun;195(6):387-9.

PMID:7644786
Abstract

Hepatic lesions induced by non-steroid antiinflammatory drugs are a common cause of disease, particularly among elderly patients. Although its clinical expression is polymorphous, occasional increases in serum transaminase values predominate. Sixteen cases of liver involvement by bendazac were studied. This NSAID is used in Spain for the treatment of cataracts, from a total of 112 patients observing such therapy. The clinical spectrum of liver disease induced by bendazac is discussed and emphasis is placed on the necessity to judiciously select the indications for NSAIDs.

摘要

非甾体抗炎药引起的肝损伤是一种常见的疾病原因,在老年患者中尤为常见。尽管其临床表现多样,但血清转氨酶值偶尔升高较为常见。对16例苄达酸引起的肝脏受累病例进行了研究。这种非甾体抗炎药在西班牙用于治疗白内障,共有112例患者接受了这种治疗。讨论了苄达酸引起的肝病的临床谱,并强调了谨慎选择非甾体抗炎药适应症的必要性。

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