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[主动脉的解剖病理学累及对Bentall手术结果的影响]

[Influence of anatomo-pathological involvement of the aorta on results of Bentall's operation].

作者信息

Dervanian P, Macé L, Le Bret E, Folliguet T A, Grinda J M, Neville P, Nakamura T, Guluta V, Neveux J Y

机构信息

Service de chirurgie cardiovasculaire et cardiaque pédiatrique, centre chirurgical Marie-Lannelongue et université Paris.

出版信息

Arch Mal Coeur Vaiss. 1995 Jan;88(1):57-62.

PMID:7646250
Abstract

The results of 51 patients undergoing the Bentall procedure for aneurysmal pathology of the ascending aorta during the last 10 years are analysed with respect to the nature of the pathology of the lesions of the arterial wall. The study population comprised 39 men and 12 women with a mean age of 47 +/- 17 years (range 2-76 years). They were divided into two groups, Group I (n = 38) with degenerative cystic medianecrosis, Group II (n = 13) with atheromatous lesions. The overall results were satisfactory with a hospital mortality of 3.9% and 5 and 10 year survival rates of 94 and 74% respectively. No difference in results was observed with respect to the anatomical site of the aneurysm, the presence of dissection or the technique used for repair. The results in degenerative lesions (Group I) were excellent but the accent should be placed on prevention to reduce the number of patients operated in a context of acute dissection. The presence of atheromatous lesions identifies a high risk group (Group II) due to advanced age, hypertension and associated vascular and coronary lesions. The hospital mortality in this group was 15.4% compared to almost nil when the aneurysmal pathology was due to degenerative lesions of the media. The extramortality of this group is directly related to the presence of atheromatous lesions (mesenteric infarction due to atheromatous embolism) and incites special attention to the mesenteric sphere in the postoperative period. The preoperative work-up should include transoesophageal echocardiography of the thoracic aortic wall, probably the source of the postoperative emboli.

摘要

分析了过去10年中51例因升主动脉瘤性病变接受Bentall手术患者的结果,涉及动脉壁病变的病理性质。研究人群包括39名男性和12名女性,平均年龄47±17岁(范围2 - 76岁)。他们被分为两组,第一组(n = 38)为退行性囊性中层坏死,第二组(n = 13)为动脉粥样硬化病变。总体结果令人满意,医院死亡率为3.9%,5年和10年生存率分别为94%和74%。在动脉瘤的解剖部位、夹层的存在或修复所用技术方面,未观察到结果差异。退行性病变(第一组)的结果极佳,但应重点放在预防上,以减少在急性夹层情况下接受手术的患者数量。动脉粥样硬化病变的存在确定了一个高危组(第二组),原因是年龄较大、高血压以及相关的血管和冠状动脉病变。该组的医院死亡率为15.4%,而当动脉瘤性病变是由于中层的退行性病变时几乎为零。该组的额外死亡率直接与动脉粥样硬化病变的存在(动脉粥样硬化栓塞导致的肠系膜梗死)相关,并促使在术后特别关注肠系膜区域。术前检查应包括经食管超声心动图检查胸主动脉壁,这可能是术后栓子的来源。

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