Seyal M, Ro T, Rafal R
Department of Neurology, University of California, Davis, Sacramento, USA.
Ann Neurol. 1995 Aug;38(2):264-7. doi: 10.1002/ana.410380221.
Transcranial magnetic stimulation of the sensorimotor cortex results in decreased sensitivity of threshold electrical stimuli to fingers of the contralateral hand. It has been suggested that one factor contributing to neglect contralateral to a unilateral parietal lesion is a release of the normal hemisphere from reciprocal interhemispheric inhibition by the damaged hemisphere. Consistent with this account, the current study demonstrated that transcranial magnetic stimulation over the parietal cortex results in increased sensitivity to cutaneous stimulation ipsilateral to the stimulation. The likely mechanism is a transcranial magnetic stimulation-induced transient dysfunction of the ipsilateral parietal cortex that then results in disinhibition of the contralateral parietal cortex.
经颅磁刺激感觉运动皮层会导致对侧手部手指的阈下电刺激敏感性降低。有人提出,导致单侧顶叶病变对侧忽视的一个因素是,受损半球对正常半球的相互半球间抑制作用解除。与这一观点一致的是,当前研究表明,经颅磁刺激顶叶皮层会导致对侧皮肤刺激的敏感性增加。可能的机制是经颅磁刺激诱发的同侧顶叶皮层短暂性功能障碍,进而导致对侧顶叶皮层去抑制。