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[关于人类惊吓性癫痫的神经生理病理学假说]

[Neurophysiopathological hypothesis on startle epilepsy in man].

作者信息

Bancaud J, Talairach J, Lamarche M, Bonis A, Trottier S

出版信息

Rev Neurol (Paris). 1975 Aug;131(8):559-71.

PMID:766135
Abstract

Clinical observation and S.E.E.G. recordings performed with a surgical purpose in a typical case of startle-epilepsy has led to a reassessment of the relationship of this form of epilepsy and "Startle reaction". It is confirmed that the critical discharges take origin in the primary motor cortex. The authors discuss, in the light of experimental data already published, the physiopathological hypotheses likely to lead to a better understanding of startle epilepsy. On the one hand it is suggested that the startle reaction may be responsible through a feed-back mechanism for triggering the epileptogenic focus. On the other hand it is assumed that afferent pathways, central organization and efferent systems involved in startle reaction and actual fits are different.

摘要

对一例典型惊吓性癫痫病例进行的以手术为目的的临床观察和立体定向脑电图记录,促使人们重新评估这种癫痫形式与“惊吓反应”之间的关系。现已证实,关键性放电起源于初级运动皮层。作者根据已发表的实验数据,讨论了可能有助于更好地理解惊吓性癫痫的生理病理假说。一方面,有人提出惊吓反应可能通过反馈机制引发致痫灶。另一方面,有人认为参与惊吓反应和实际发作的传入通路、中枢组织和传出系统是不同的。

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