Burrows N P, Jones D H, Hudson P M, Pye R J
Department of Dermatology, Addenbrooke's Hospital, Cambridge, UK.
Br J Dermatol. 1995 Jun;132(6):970-2. doi: 10.1111/j.1365-2133.1995.tb16957.x.
Extramammary Paget's disease (EMPD) is a rare cutaneous malignancy, which usually occurs in the elderly. Wide local excision is the recommended treatment, although this may not always be feasible. We report our experience of EMPD treated by radiotherapy in five patients. The radiotherapy was well tolerated in each case, and there were no signs of recurrence during follow-up (6 months-8 years). This study shows that radiotherapy is a useful alternative therapy for EMPD, and should be considered particularly in elderly patients who may not tolerate surgery.
乳房外佩吉特病(EMPD)是一种罕见的皮肤恶性肿瘤,通常发生于老年人。推荐的治疗方法是广泛局部切除,尽管这并非总是可行。我们报告了5例接受放射治疗的EMPD患者的治疗经验。每例患者对放射治疗耐受性良好,随访期间(6个月至8年)均无复发迹象。本研究表明,放射治疗是EMPD的一种有效替代疗法,对于无法耐受手术的老年患者尤其应考虑采用。