出生后72小时内非窘迫早产婴儿的肾血流速度。

Renal blood flow velocity in non-distressed preterm infants during the first 72 hours of life.

作者信息

van de Bor M

机构信息

Department of Pediatrics, University Hospital Leiden, The Netherlands.

出版信息

Biol Neonate. 1995;67(5):346-51. doi: 10.1159/000244184.

DOI:10.1159/000244184

PMID:7662814

Abstract

Renal blood flow velocity (RBFV) was studied with two-dimensional/pulsed Doppler ultrasound in 28 non-distressed very preterm infants (mean +/- SD gestational age was 27.3 +/- 2.1 weeks and birth weight 907 +/- 214 g) at 6, 12, 24, 36, 48, and 72 h of age. Mean arterial blood pressure (MABP), PaCO2, PaO2, and Hct were determined simultaneously. Mean RBFV increased significantly from 14.5 +/- 1.9 cm/s at 6 h to 20.2 +/- 2.5 cm/s at 72 h (p < 0.005). MABP decreased slightly though significantly between 6 h (36.5 +/- 1.8 mm Hg) and 12 h (34.3 +/- 1.5 mm Hg), but rose thereafter to significantly higher values at 72 h (41.4 +/- 1.3 mm Hg). Renal vascular resistance (RVR = MABP/RBFV) decreased rapidly during the first day of life (2.6 +/- 0.1 mm Hg/cm.s-1 at 6 h vs. 2.0 +/- 0.05 mm Hg/cm.s-1 at 24 h). In conclusion, RBFV increases whereas RVR decreases during the first days of life.

摘要

采用二维/脉冲多普勒超声对28例无窘迫的极早产儿（平均胎龄±标准差为27.3±2.1周，出生体重907±214g）在出生后6、12、24、36、48和72小时进行肾血流速度（RBFV）研究。同时测定平均动脉血压（MABP）、动脉血二氧化碳分压（PaCO2）、动脉血氧分压（PaO2）和血细胞比容（Hct）。平均RBFV从6小时时的14.5±1.9cm/s显著增加至72小时时的20.2±2.5cm/s（p<0.005）。MABP在6小时（36.5±1.8mmHg）至12小时（34.3±1.5mmHg）之间略有下降但差异有统计学意义，之后在72小时升至显著更高水平（41.4±1.3mmHg）。肾血管阻力（RVR = MABP/RBFV）在出生后第一天迅速下降（6小时时为2.6±0.1mmHg/cm·s-1，24小时时为2.0±0.05mmHg/cm·s-1）。总之，出生后第一天RBFV增加而RVR下降。