Van Der Wielen N J, Dorresteijn J, Frik J F, Kersjes A W, Wensing T H
Tijdschr Diergeneeskd. 1976 Mar 15;101(6).
The development of polyarthritis was studied in thirty-six calves. Thirty patients were from two to eleven days of age; six animals were older than eleven days. Besides clinical studies, the synovial fluid was examined both biochemically and bacteriologically in addition, a blood culture was made. When the synovial fluids of twenty-six calves were studied bacteriologically, P. multocida was isolated in ten cases, P. haemolytica in two cases, E. coli in ten cases, streptococci in three cases and D. pneumoniae in one case; bacteriological examination of the synovial fluid was negative in ten cases. Blood cultures were positive in twenty animals (P. multocida in five cases, P. haemolytica in two cases, E. coli in eleven cases, S. subacidus in one case and D. pneumoniae in one case). Twenty-five calves were treated by intra-articular as well as intramuscular injection of kanamycin (sulphate); six animals were treated with similar injections of ampicillin. Treatment with ampicillin was initially instituted in five calves; after some time, however, kanamycine (sulphate) was substituted for this medication. Twenty-seven calves recovered completely.
对36头犊牛的多关节炎发病情况进行了研究。30头犊牛年龄在2至11日龄之间;6头动物年龄超过11日龄。除临床研究外,还对滑液进行了生化和细菌学检查,另外还进行了血培养。对26头犊牛的滑液进行细菌学研究时,10例分离出多杀性巴氏杆菌,2例分离出溶血巴氏杆菌,10例分离出大肠杆菌,3例分离出链球菌,1例分离出肺炎双球菌;10例滑液细菌学检查为阴性。20头动物血培养呈阳性(5例为多杀性巴氏杆菌,2例为溶血巴氏杆菌,11例为大肠杆菌,1例为嗜酸乳杆菌,1例为肺炎双球菌)。25头犊牛通过关节内及肌肉注射硫酸卡那霉素进行治疗;6头动物用类似的氨苄西林注射治疗。最初对5头犊牛使用氨苄西林治疗;然而,一段时间后,用硫酸卡那霉素替代了这种药物。27头犊牛完全康复。