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[弹性假黄瘤合并不稳定型心绞痛和勒里什综合征:一例报告]

[Pseudoxanthoma elasticum associated with unstable angina and Leriche syndrome: a case report].

作者信息

Hiragi T, Yoshikawa J, Okura H, Honda Y, Akasaka T

机构信息

Department of Cardiology, Kobe General Hospital.

出版信息

J Cardiol. 1995 Jul;26(1):43-9.

PMID:7666344
Abstract

A 64-year-old man with a history of intermittent claudication presented with chest pain. On admission, he had yellowish papules with a "plucked chicken" appearance on his neck. Histological examination of the biopsy specimen of the lesion revealed degeneration and calcification of elastic fibers in the dermis. His daughter also had similar histological changes in the skin. The diagnosis was pseudoxanthoma elasticum. Fundoscopic examination revealed angioid streaks. Electrocardiography showed inverted T waves in V2-V6, and echocardiography revealed hypokinesis in the anterior wall of the left ventricle. Emergency catheterization showed 90% stenosis in the left anterior descending coronary artery, total occlusion of the abdominal aorta, and severe stenosis in the right subclavian artery. He was treated medically and had no recurrent episodes of chest pain. A careful examination for cardiovascular diseases should be considered in patients with pseudoxanthoma elasticum.

摘要

一名有间歇性跛行病史的64岁男性因胸痛就诊。入院时,他颈部有呈“拔毛鸡”外观的淡黄色丘疹。病变活检标本的组织学检查显示真皮层弹性纤维变性和钙化。他的女儿皮肤也有类似的组织学变化。诊断为弹性假黄瘤。眼底检查发现血管样条纹。心电图显示V2-V6导联T波倒置,超声心动图显示左心室前壁运动减弱。急诊导管检查显示左前降支冠状动脉狭窄90%,腹主动脉完全闭塞,右锁骨下动脉严重狭窄。他接受了药物治疗,未再出现胸痛发作。对于弹性假黄瘤患者,应考虑仔细检查心血管疾病。

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