McGlashan T H, Carpenter W T
Arch Gen Psychiatry. 1976 Feb;33(2):231-9. doi: 10.1001/archpsyc.1976.01770020065011.
Several authors have described a severe depression in patients emerging from psychotic states. The clinical picture usually resembles that of a retarded depression with strong neurasthenic and schizoid components. It frequently emerges after a patient has been discharged from the hospital and may often go unnoticed. When manifest, the syndrome is usually stable phenomenologically, is often lengthy, and may be resistant to all modalities of treatment. Postpsychotic depression is a relatively neglected clinical area despite the risk of suicide and prolonged suffering. Therapeutic perseverence purportedly can improve the patient's long-term prognosis, and the phenomenon itself may be favorable prognostic sign. We present here a review and reformulation of this syndrome.
几位作者描述了从精神病状态中恢复的患者出现的严重抑郁。临床表现通常类似于伴有强烈神经衰弱和类精神分裂症成分的迟发性抑郁。它经常在患者出院后出现，且可能常常未被注意到。当症状明显时，该综合征在现象学上通常是稳定的，病程往往较长，并且可能对所有治疗方式都有抵抗性。尽管存在自杀风险和长期痛苦，但精神病后抑郁仍是一个相对被忽视的临床领域。据称坚持治疗可以改善患者的长期预后，而且这种现象本身可能是一个良好的预后标志。我们在此对该综合征进行综述并重新阐述。
