多功能吲哚 - 3 - 甲醇衍生物：1 -（吲哚 - 3 - 基）甘油及其相关化合物、β - 羟基色胺和抗坏血酸原。化学与生物学性质
Polyfunctional indole-3-carbinol derivatives: 1-(indol-3-yl)glycerols and related compounds, beta-hydroxytryptamines and ascorbigens. Chemistry and biological properties.
作者信息
Preobrazhenskaya M N, Korolev A M, Isaeva N N, Lazhko E I, Lomidze L A
机构信息
Institute of New Antibiotics of the Russian Academy of Medical Sciences Moscow.
出版信息
Farmaco. 1995 Jun;50(6):369-77.
Earlier interaction of indole-3-carbinols with L-ascorbic acid and chemical and biological properties of formed 2-skatylderivatives of L-ascorbic acid (ascorbigens) were discussed. In this presentation the properties and stereochemistry of products of interaction of polyfunctional biologically important indole-3-carbinols (indoleglycerol analogs and beta-hydroxytryptamine derivatives) with L-ascorbic acid are investigated. Biological significance of this reaction is discussed.
此前已讨论过吲哚 - 3 - 甲醇与L - 抗坏血酸的早期相互作用以及所形成的L - 抗坏血酸的2 - 甲基吲哚衍生物（抗坏血原）的化学和生物学性质。在本报告中，研究了多功能生物重要吲哚 - 3 - 甲醇（吲哚甘油类似物和β - 羟基色胺衍生物）与L - 抗坏血酸相互作用产物的性质和立体化学。并讨论了该反应的生物学意义。
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